↓ Skip to main content

Filopodyan: An open-source pipeline for the analysis of filopodia

Overview of attention for article published in Journal of Cell Biology, July 2017
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

twitter
39 X users
facebook
6 Facebook pages

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
105 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Filopodyan: An open-source pipeline for the analysis of filopodia
Published in
Journal of Cell Biology, July 2017
DOI 10.1083/jcb.201705113
Pubmed ID
Authors

Vasja Urbančič, Richard Butler, Benjamin Richier, Manuel Peter, Julia Mason, Frederick J. Livesey, Christine E. Holt, Jennifer L. Gallop

Abstract

Filopodia have important sensory and mechanical roles in motile cells. The recruitment of actin regulators, such as ENA/VASP proteins, to sites of protrusion underlies diverse molecular mechanisms of filopodia formation and extension. We developed Filopodyan (filopodia dynamics analysis) in Fiji and R to measure fluorescence in filopodia and at their tips and bases concurrently with their morphological and dynamic properties. Filopodyan supports high-throughput phenotype characterization as well as detailed interactive editing of filopodia reconstructions through an intuitive graphical user interface. Our highly customizable pipeline is widely applicable, capable of detecting filopodia in four different cell types in vitro and in vivo. We use Filopodyan to quantify the recruitment of ENA and VASP preceding filopodia formation in neuronal growth cones, and uncover a molecular heterogeneity whereby different filopodia display markedly different responses to changes in the accumulation of ENA and VASP fluorescence in their tips over time.

X Demographics

X Demographics

The data shown below were collected from the profiles of 39 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 105 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 24%
Researcher 15 14%
Student > Master 15 14%
Student > Bachelor 11 10%
Student > Doctoral Student 7 7%
Other 15 14%
Unknown 17 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 26 25%
Agricultural and Biological Sciences 23 22%
Neuroscience 12 11%
Physics and Astronomy 6 6%
Engineering 5 5%
Other 13 12%
Unknown 20 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2020.
All research outputs
#1,566,564
of 24,647,023 outputs
Outputs from Journal of Cell Biology
#771
of 11,825 outputs
Outputs of similar age
#30,867
of 320,916 outputs
Outputs of similar age from Journal of Cell Biology
#15
of 108 outputs
Altmetric has tracked 24,647,023 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,825 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,916 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 108 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.